The club, founded by Palestinians in Santiago, Chile, in 1920, was leading 1-0 at Universidad Catolica when it was reduced to 10 men after Julian Rodrigo Fernandez was shown a straight red card.
Copa Sudamericana kicks off with high drama
There was drama aplenty as the Copa Sudamericana kicked off in South America, with four teams putting themselves into the group stages from the first round, including 10-man Palestino.
Then two minutes from time, Fernando Zampedri equalised for the hosts, sending the match to a penalty shootout.
But Palestino held its nerve and won the shootout 5-4 to progress.
Another dramatic shootout saw Cienciano get through its first-round tie against ADT when it looked like never making it out of the first round.
